The formulation is a mixture of several different alkyl sulfate chain lengths c10 to c18. Physical and chemical properties molecular formula nac12h25oso3. American elements produces to many standard grades when applicable, including mil spec military grade. Since the sodium ion has more activity than the potassium ion, i. Material safety data sheet sodium sulfate anhydrous. This sds does not contain any contaminating ions that might impair. The gross conformation of proteinsodium dodecyl sulfate. Sodium lauryl sulfate dodecyl sodium sulfate dodecyl sulfatesodium salt sds formula. Sodium dodecyl sulfate sds in the presence of excess sodium chloride nacl or calcium. Sodium dodecyl sulfate sds, also known as lauryl sulfate, is an ionic detergent that is useful for the rapid disruption of biological membranes.
It may be dangerous to the person providing aid to give mouthtomouth resuscitation. The micelles formed by sodium dodecyl sulfate sds are studied in aqueous solutions at 294 k as a function of nominal sds concentration c using positron lifetime spectroscopy. The binding of sodium dodecyl sulphate to various proteins. Ntp, 1992 salts, basic, such as dodecyl sulfate, are generally soluble in water. Product consists of 10% w v sodium dodecyl sulfate sds. Sodium dodecyl sulfate sds is an alkyl sulfate, anionic detergent used frequently in protein electrophoresis and protein solubilization methods. Pronunciation of sodium dodecyl sulfate with 2 audio pronunciations, 12 translations and more for sodium dodecyl sulfate. It is also incompatible with cationic materials and with acids with ph below 2. Sodium dodecyl sulfate sds, white powder, electrophoresis. Sodium lauryl sulfate 1288 mgkg rat 580 mgkg rabbit 3900 mgm3 rat 1 h sodium sulfate 0 mgkg rat not listed not listed sodium chloride 3 gkg rat 10 gkg rabbit 42 gm3 rat 1 h irritation irritating to eyes, respiratory system and skin toxicologically synergistic products no information available. It has a role as a detergent and a protein denaturant.
Take account of environmentally hazardous firefighting water. Sodium dodecyl sulfate or sodium dodecylsulfate is generally immediately available in most volumes. Uses advised against not for food, drug, pesticide or biocidal product use. Sodium dodecyl sulfate safety data sheet according to federal register vol.
As can be seen from scheme 2, a sodium ion replaces the potassium ion. It is an anionic surfactant used in many cleaning and hygiene products. Pdf toxicity of sodium dodecyl sulfate to federally. Identification product name sodium lauryl sulfate nffcc cat no.
Sds solution 10% safety data sheet university of reading. Dodecyl sulfate is incompatible with strong oxidizers. Sodium dodecyl sulfate sds, 10% solution wash out mouth with water. The interaction of sodium dodecyl sulfate with a wide variety of proteins is characterized by a high binding ratio when the monomer concentration of amphiphile exceeds 5 x 10w4 m. Warning this product is not for human or veterinary use.
If diluted with water, this chemical released directly or indirectly into the environment is not expected to have a significant impact. Sigmaaldrich offers a number of sodium dodecyl sulfate solution products. The light influences the dynamic surface tension of. This binding ratio on a gram to gram basis is identi cal for all proteins investigated. Sodium dodecyl sulfate sds, c12 thermo fisher scientific. Stop if the exposed person feels sick as vomiting may be. The glycoproteins studied bound 70100% of their weight of sodium dodecyl sulphate, calculated in terms of the polypeptide moiety of the molecule. Various characterization techniques revealed that the. Sodium lauryl sulfate sulfuric acid monododecyl ester sodium salt.
Sodium lauryl sulfate is a mixture of sodium alkyl sulfates consisting chiefly of sodium lauryl sulfate ch 3 ch 2 10 ch 2 oso 3 na. Sodium dodecyl sulfate an overview sciencedirect topics. Sodium dodecyl sulfate sds also known as sodium lauryl sulfate is an anionic surfactant solution used as an adjuvant in lysing cells during dna extraction e. The effect of glycerol on both micellar formation and the structural evolution of the sodium dodecyl sulfate sds aggregates in the context of the action mechanism of the cosolvent has been studied. Pdf structure of pure sds and dtab micelles in brine determined. Concentration sodium dodecyl sulphate 1512 2057881 4. Keep container tightly closed in a cool, wellventilated place.
Size of sodium dodecyl sulfate micelles in aqueous solutions. Choose from over 850 chemical products in chemical grades, sizes and concentrations to meet your needs. See section 8 of the msds for personal protective equipment. This assay was originally adapted to be used with methylene blue 1 however. Box 326 gilbertsville, pa 19512 emergency telephone number. It is a component of many cell lysis buffer formulations, including ripa buffer. It is a key component of many reagents used to purify nucleic acids because of its abilities to quickly disrupt the tissue architecture and to inhibit both rnase and deoxyribonuclease dnase activity. Show this safety data sheet to the doctor in attendance. This allows for relatively linear separation in electrophoresis, most often page polyacrylamide gel electrophoresis, sodium lauryl sulfate. Sulfuric acid, monodecyl ester, sodium salt cas no 1512 molecular weight. Dodecyl sodium sulfate dodecyl sulfatesodium salt sds formula. Sodium dodecyl sulfate is an organic sodium salt that is the sodium salt of dodecyl hydrogen sulfate. Sds solution, 20% sodium dodecyl sulfate solution, molecular.
Sodium dodecyl sulfate sds 10% wv stock solution contains 10% sodium dodecyl sulfate. Sodium dodecyl sulfate 10% wv stock solution safety data sheet supersedes revision. Dodecyl sodium sulfate recommended use laboratory chemicals. Request pdf ionic surfactant aggregates in saline solutions. Sodium dodecyl sulfate 10% wv stock solution safety data. Typical sds or lauryl sulfate preparations are mixtures of several different chain lengths c10 to c18. The substance identity section is calculated from substance identification information from all echa databases. The rigidification of the shell membrane of microcapsules was achieved by alkali treatment in the presence of a small amount of 1butanol to reduce aggregation. Remove victim to fresh air and keep at rest in a position comfortable for breathing. Sodium dodecyl sulphate substance information echa. Sds represents a potentially effective topical microbicide, which can also inhibit and possibly prevent infection by various enveloped and nonenveloped viruses such as.
Sodium dodecyl sulfate sds, a surfactant with no usepawater quality criteria wqc, is commonly used in industrial applications, household cleaners, personal hygiene products, and herbicides. Effect of light on selfassembly of aqueous mixtures of. Exposure controlspersonal protection control parameters. Polyacrylamide gel electrophoresis is used for the qualitative characterisation of 5 proteins in biological preparations, for control of purity and for quantitative determinations. Sodium lauryl sulfate, in science referred to as sodium dodecyl sulfate sds or duponol, is commonly used in preparing proteins for electrophoresis in the sdspage technique. The substance identifiers displayed in the infocard are the best available substance name, ec number, cas number andor the molecular and structural formulas. Effects of butanol during alkali treatment and citrate in post alkali treatment were monitored in terms of morphology and the chemical properties of microcapsules. Sodium dodecyl sulfate product number l 3771 storage temperature rt product description molecular formula. Sodium dodecyl sulfate sds or sodium lauryl sulfate sls, sometimes written sodium laurilsulfate, is a synthetic organic compound with the formula c h 3 ch 2 11 so 4 na. We report the use of uv light to control the dynamic surface tensions of mixed surfactant systems containing sodium dodecyl sulfate, sds, and 4,4bistrimethylammoniumhexyloxyazobenzene bromide, btha. No action shall be taken involving any personal risk or without suitable training.
Sodium dodecyl sulfate sds, white powder, electrophoresis, fisher bioreagents for protein extraction procedures and sds polyacrylamide gels brand. Synonyms sodium dodecyl sulfate buffer, sodium laurilsulfate buffer, sds buffer application note this product is a concentrated stock solution and should be diluted appropriately with distilled, deionized water or equivalent to its final working concentration. The substance identifiers displayed in the infocard are the best available substance name, ec number, cas number andor the. Sds sodium dodecylsulfate catalog or product number. This laurylgrade sodium dodecyl sulfate sds is a popular anionic detergent for routine protein electrophoresis and cell lysis methods. The binding of sodium dodecyl sulphate to proteins by equilibrium dialysis was investigated. A twice recrystallized quality of sds with excellent qualities for denaturing proteins before gel electrophoresis, molecular weight sieving and many other applicationsharewood k.
Sodium sulfate may persist indefinitely in the environment, but is not likely to show bioaccumulation or food chain contamination effects. Carolina offers the highest quality kits for a handson approach within ap chemistry classrooms. First aid measures general advice consult a physician. Dodecyl sulfate, sodium salt appears as white to pale yellow paste or liquid with a mild odor. Most of the proteins studied bound 90100% of their weight of sodium dodecyl sulphate. If material has been swallowed and the exposed person is conscious, give small quantities of water to drink. Conditions for safe storage, including any incompatibilities. Identification of the substancemixture and of the companyundertaking product name. Sodium dodecyl sulfate sds potassium dodecyl sulfate pds scheme 2. Identification of the substancemixture and of the companyundertaking 1. Sds is used to denature proteins with a fixed single negative charge per approximately 2 amino acids. Health effect of inhaling sds sodium dodecyl sulphate category. Sigmaaldrich material safety data sheet date printed.
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